diff --git a/pkg/compiler/analysis.go b/pkg/compiler/analysis.go
index bf4430c74..6c052e5af 100644
--- a/pkg/compiler/analysis.go
+++ b/pkg/compiler/analysis.go
@@ -17,6 +17,7 @@ var (
 		"VerifySignature", "AppCall",
 		"FromAddress", "Equals",
 		"panic", "DynAppCall",
+		"delete", "Remove",
 	}
 )
 
diff --git a/pkg/compiler/codegen.go b/pkg/compiler/codegen.go
index 032d3d2f1..c53282399 100644
--- a/pkg/compiler/codegen.go
+++ b/pkg/compiler/codegen.go
@@ -1075,6 +1075,19 @@ func (c *codegen) convertBuiltin(expr *ast.CallExpr) {
 		} else {
 			c.prog.Err = errors.New("panic should have string or nil argument")
 		}
+	case "delete", "Remove":
+		arg := expr.Args[0]
+		errNotSupported := errors.New("only maps and non-byte slices are supported in `Remove`")
+		switch typ := c.typeInfo.Types[arg].Type.Underlying().(type) {
+		case *types.Map:
+		case *types.Slice:
+			if isByte(typ.Elem()) {
+				c.prog.Err = errNotSupported
+			}
+		default:
+			c.prog.Err = errNotSupported
+		}
+		emit.Opcode(c.prog.BinWriter, opcode.REMOVE)
 	case "SHA256":
 		emit.Opcode(c.prog.BinWriter, opcode.SHA256)
 	case "SHA1":
diff --git a/pkg/compiler/interop_test.go b/pkg/compiler/interop_test.go
index e335f5882..1b2e3539d 100644
--- a/pkg/compiler/interop_test.go
+++ b/pkg/compiler/interop_test.go
@@ -2,6 +2,7 @@ package compiler_test
 
 import (
 	"fmt"
+	"math/big"
 	"strings"
 	"testing"
 
@@ -13,6 +14,56 @@ import (
 	"github.com/stretchr/testify/require"
 )
 
+func TestRemove(t *testing.T) {
+	srcTmpl := `package foo
+	import "github.com/nspcc-dev/neo-go/pkg/interop/util"
+	func Main() int {
+		a := %s
+		util.Remove(a, %d)
+		return len(a) * a[%d]
+	}`
+	testRemove := func(item string, key, index, result int64) func(t *testing.T) {
+		return func(t *testing.T) {
+			src := fmt.Sprintf(srcTmpl, item, key, index)
+			if result > 0 {
+				eval(t, src, big.NewInt(result))
+				return
+			}
+			v := vmAndCompile(t, src)
+			require.Error(t, v.Run())
+		}
+	}
+	t.Run("Map", func(t *testing.T) {
+		item := "map[int]int{1: 2, 5: 7, 11: 13}"
+		t.Run("RemovedKey", testRemove(item, 5, 5, -1))
+		t.Run("AnotherKey", testRemove(item, 5, 11, 26))
+	})
+	t.Run("Slice", func(t *testing.T) {
+		item := "[]int{5, 7, 11, 13}"
+		t.Run("RemovedKey", testRemove(item, 2, 2, 39))
+		t.Run("AnotherKey", testRemove(item, 2, 1, 21))
+		t.Run("LastKey", testRemove(item, 2, 3, -1))
+	})
+	t.Run("Invalid", func(t *testing.T) {
+		srcTmpl := `package foo
+		import "github.com/nspcc-dev/neo-go/pkg/interop/util"
+		func Main() int {
+			util.Remove(%s, 2)
+			return 1
+		}`
+		t.Run("BasicType", func(t *testing.T) {
+			src := fmt.Sprintf(srcTmpl, "1")
+			_, err := compiler.Compile(strings.NewReader(src))
+			require.Error(t, err)
+		})
+		t.Run("ByteSlice", func(t *testing.T) {
+			src := fmt.Sprintf(srcTmpl, "[]byte{1, 2}")
+			_, err := compiler.Compile(strings.NewReader(src))
+			require.Error(t, err)
+		})
+	})
+}
+
 func TestFromAddress(t *testing.T) {
 	as1 := "Aej1fe4mUgou48Zzup5j8sPrE3973cJ5oz"
 	addr1, err := address.StringToUint160(as1)
diff --git a/pkg/interop/util/util.go b/pkg/interop/util/util.go
index 1aba144cb..a87ea200a 100644
--- a/pkg/interop/util/util.go
+++ b/pkg/interop/util/util.go
@@ -17,3 +17,8 @@ func FromAddress(address string) []byte {
 func Equals(a, b interface{}) bool {
 	return false
 }
+
+// Remove removes item with the specified key from slice or map.
+// For maps it is similar to `delete`.
+// For slices it performs mutable update as if slice was provided by pointer.
+func Remove(sliceOrMap, key interface{}) {}