diff --git a/pkg/vm/stackitem/item.go b/pkg/vm/stackitem/item.go
index 8e5952a46..7f86879b5 100644
--- a/pkg/vm/stackitem/item.go
+++ b/pkg/vm/stackitem/item.go
@@ -132,6 +132,16 @@ func Make(v any) Item {
 		return Make(val.BytesBE())
 	case util.Uint256:
 		return Make(val.BytesBE())
+	case *util.Uint160:
+		if val == nil {
+			return Null{}
+		}
+		return Make(*val)
+	case *util.Uint256:
+		if val == nil {
+			return Null{}
+		}
+		return Make(*val)
 	case nil:
 		return Null{}
 	default:
diff --git a/pkg/vm/stackitem/item_test.go b/pkg/vm/stackitem/item_test.go
index c90763b84..afdfee213 100644
--- a/pkg/vm/stackitem/item_test.go
+++ b/pkg/vm/stackitem/item_test.go
@@ -5,6 +5,7 @@ import (
 	"testing"
 
 	"github.com/nspcc-dev/neo-go/pkg/encoding/bigint"
+	"github.com/nspcc-dev/neo-go/pkg/util"
 	"github.com/stretchr/testify/assert"
 	"github.com/stretchr/testify/require"
 )
@@ -81,6 +82,22 @@ var makeStackItemTestCases = []struct {
 		input:  nil,
 		result: Null{},
 	},
+	{
+		input:  &util.Uint160{1, 2, 3},
+		result: NewByteArray(util.Uint160{1, 2, 3}.BytesBE()),
+	},
+	{
+		input:  &util.Uint256{1, 2, 3},
+		result: NewByteArray(util.Uint256{1, 2, 3}.BytesBE()),
+	},
+	{
+		input:  (*util.Uint160)(nil),
+		result: Null{},
+	},
+	{
+		input:  (*util.Uint256)(nil),
+		result: Null{},
+	},
 }
 
 var makeStackItemErrorCases = []struct {