diff --git a/rpc/client/call_options.go b/rpc/client/call_options.go
new file mode 100644
index 00000000..ef849f33
--- /dev/null
+++ b/rpc/client/call_options.go
@@ -0,0 +1,27 @@
+package client
+
+import (
+	"context"
+
+	"github.com/nspcc-dev/neofs-api-go/rpc/grpc"
+)
+
+// CallOption is a messaging session option within Protobuf RPC.
+type CallOption func(*callParameters)
+
+type callParameters struct {
+	callOpts []grpc.CallOption
+}
+
+func defaultCallParameters() *callParameters {
+	return &callParameters{
+		callOpts: make([]grpc.CallOption, 0, 1),
+	}
+}
+
+// WithContext return options to specify call context.
+func WithContext(ctx context.Context) CallOption {
+	return func(prm *callParameters) {
+		prm.callOpts = append(prm.callOpts, grpc.WithContext(ctx))
+	}
+}
diff --git a/rpc/client/client.go b/rpc/client/client.go
new file mode 100644
index 00000000..e51cdcf5
--- /dev/null
+++ b/rpc/client/client.go
@@ -0,0 +1,29 @@
+package client
+
+import (
+	"sync"
+
+	"github.com/nspcc-dev/neofs-api-go/rpc/grpc"
+)
+
+// Client represents client for exchanging messages
+// with a remote server using Protobuf RPC.
+type Client struct {
+	*cfg
+
+	gRPCClientOnce sync.Once
+	gRPCClient     *grpc.Client
+}
+
+// New creates, configures via options and returns new Client instance.
+func New(opts ...Option) *Client {
+	c := defaultCfg()
+
+	for _, opt := range opts {
+		opt(c)
+	}
+
+	return &Client{
+		cfg: c,
+	}
+}
diff --git a/rpc/client/connect.go b/rpc/client/connect.go
new file mode 100644
index 00000000..f9cd940e
--- /dev/null
+++ b/rpc/client/connect.go
@@ -0,0 +1,41 @@
+package client
+
+import (
+	"context"
+	"errors"
+
+	"github.com/nspcc-dev/neofs-api-go/rpc/grpc"
+	grpcstd "google.golang.org/grpc"
+)
+
+func (c *Client) createGRPCClient() (err error) {
+	c.gRPCClientOnce.Do(func() {
+		if err = c.openGRPCConn(); err != nil {
+			return
+		}
+
+		c.gRPCClient = grpc.New(grpc.WithClientConnection(c.conn))
+	})
+
+	return
+}
+
+var errInvalidEndpoint = errors.New("invalid endpoint options")
+
+func (c *Client) openGRPCConn() error {
+	if c.conn != nil {
+		return nil
+	}
+
+	if c.addr == "" {
+		return errInvalidEndpoint
+	}
+
+	var err error
+
+	dialCtx, cancel := context.WithTimeout(context.Background(), c.dialTimeout)
+	c.conn, err = grpcstd.DialContext(dialCtx, c.addr, grpcstd.WithInsecure())
+	cancel()
+
+	return err
+}
diff --git a/rpc/client/flows.go b/rpc/client/flows.go
new file mode 100644
index 00000000..ceb890e7
--- /dev/null
+++ b/rpc/client/flows.go
@@ -0,0 +1,124 @@
+package client
+
+import (
+	"io"
+	"sync"
+
+	"github.com/nspcc-dev/neofs-api-go/rpc/common"
+	"github.com/nspcc-dev/neofs-api-go/rpc/message"
+	"github.com/pkg/errors"
+)
+
+// SendUnary initializes communication session by RPC info, performs unary RPC
+// and closes the session.
+func SendUnary(cli *Client, info common.CallMethodInfo, req, resp message.Message, opts ...CallOption) error {
+	rw, err := cli.Init(info, opts...)
+	if err != nil {
+		return err
+	}
+
+	err = rw.WriteMessage(req)
+	if err != nil {
+		return err
+	}
+
+	err = rw.ReadMessage(resp)
+	if err != nil {
+		return err
+	}
+
+	return rw.Close()
+}
+
+// MessageWriterCloser wraps MessageWriter
+// and io.Closer interfaces.
+type MessageWriterCloser interface {
+	MessageWriter
+	io.Closer
+}
+
+type clientStreamWriterCloser struct {
+	MessageReadWriter
+
+	resp message.Message
+}
+
+func (c *clientStreamWriterCloser) Close() error {
+	err := c.MessageReadWriter.Close()
+	if err != nil {
+		return err
+	}
+
+	return c.ReadMessage(c.resp)
+}
+
+// OpenClientStream initializes communication session by RPC info, opens client-side stream
+// and returns its interface.
+//
+// All stream writes must be performed before the closing. Close must be called once.
+func OpenClientStream(cli *Client, info common.CallMethodInfo, resp message.Message, opts ...CallOption) (MessageWriterCloser, error) {
+	rw, err := cli.Init(info, opts...)
+	if err != nil {
+		return nil, err
+	}
+
+	return &clientStreamWriterCloser{
+		MessageReadWriter: rw,
+		resp:              resp,
+	}, nil
+}
+
+// MessageReaderCloser wraps MessageReader
+// and io.Closer interface.
+type MessageReaderCloser interface {
+	MessageReader
+	io.Closer
+}
+
+type serverStreamReaderCloser struct {
+	rw MessageReadWriter
+
+	once sync.Once
+
+	req message.Message
+}
+
+func (s *serverStreamReaderCloser) ReadMessage(msg message.Message) error {
+	var err error
+
+	s.once.Do(func() {
+		err = s.rw.WriteMessage(s.req)
+	})
+
+	if err != nil {
+		return err
+	}
+
+	err = s.rw.ReadMessage(msg)
+	if !errors.Is(err, io.EOF) {
+		return err
+	}
+
+	err = s.rw.Close()
+	if err != nil {
+		return err
+	}
+
+	return io.EOF
+}
+
+// OpenServerStream initializes communication session by RPC info, opens server-side stream
+// and returns its interface.
+//
+// All stream reads must be performed before the closing. Close must be called once.
+func OpenServerStream(cli *Client, info common.CallMethodInfo, req message.Message, opts ...CallOption) (MessageReader, error) {
+	rw, err := cli.Init(info, opts...)
+	if err != nil {
+		return nil, err
+	}
+
+	return &serverStreamReaderCloser{
+		rw:  rw,
+		req: req,
+	}, nil
+}
diff --git a/rpc/client/init.go b/rpc/client/init.go
new file mode 100644
index 00000000..aa0d420b
--- /dev/null
+++ b/rpc/client/init.go
@@ -0,0 +1,83 @@
+package client
+
+import (
+	"io"
+
+	"github.com/nspcc-dev/neofs-api-go/rpc/common"
+	"github.com/nspcc-dev/neofs-api-go/rpc/grpc"
+	"github.com/nspcc-dev/neofs-api-go/rpc/message"
+)
+
+// MessageReader is an interface of the Message reader.
+type MessageReader interface {
+	// ReadMessage reads the next Message.
+	//
+	// Returns io.EOF if there are no more messages to read.
+	// ReadMessage should not be called after io.EOF occasion.
+	ReadMessage(message.Message) error
+}
+
+// MessageWriter is an interface of the Message writer.
+type MessageWriter interface {
+	// WriteMessage writers the next Message.
+	//
+	// WriteMessage should not be called after any error.
+	WriteMessage(message.Message) error
+}
+
+// MessageReadWriter is a component interface
+// for transmitting raw Protobuf messages.
+type MessageReadWriter interface {
+	MessageReader
+	MessageWriter
+
+	// Closes the communication session.
+	//
+	// All calls to send/receive messages must be done before closing.
+	io.Closer
+}
+
+// Init initiates a messaging session and returns the interface for message transmitting.
+func (c *Client) Init(info common.CallMethodInfo, opts ...CallOption) (MessageReadWriter, error) {
+	prm := defaultCallParameters()
+
+	for _, opt := range opts {
+		opt(prm)
+	}
+
+	return c.initGRPC(info, prm)
+}
+
+type rwGRPC struct {
+	grpc.MessageReadWriter
+}
+
+func (g rwGRPC) ReadMessage(m message.Message) error {
+	// Can be optimized: we can create blank message here.
+	gm := m.ToGRPCMessage()
+
+	if err := g.MessageReadWriter.ReadMessage(gm); err != nil {
+		return err
+	}
+
+	return m.FromGRPCMessage(gm)
+}
+
+func (g rwGRPC) WriteMessage(m message.Message) error {
+	return g.MessageReadWriter.WriteMessage(m.ToGRPCMessage())
+}
+
+func (c *Client) initGRPC(info common.CallMethodInfo, prm *callParameters) (MessageReadWriter, error) {
+	if err := c.createGRPCClient(); err != nil {
+		return nil, err
+	}
+
+	rw, err := c.gRPCClient.Init(info, prm.callOpts...)
+	if err != nil {
+		return nil, err
+	}
+
+	return &rwGRPC{
+		MessageReadWriter: rw,
+	}, nil
+}
diff --git a/rpc/client/options.go b/rpc/client/options.go
new file mode 100644
index 00000000..9f2a2263
--- /dev/null
+++ b/rpc/client/options.go
@@ -0,0 +1,60 @@
+package client
+
+import (
+	"time"
+
+	"google.golang.org/grpc"
+)
+
+// Option is a Client's option.
+type Option func(*cfg)
+
+type cfg struct {
+	addr string
+
+	dialTimeout time.Duration
+
+	conn *grpc.ClientConn
+}
+
+const defaultDialTimeout = 5 * time.Second
+
+func defaultCfg() *cfg {
+	return &cfg{
+		dialTimeout: defaultDialTimeout,
+	}
+}
+
+// WithNetworkAddress returns option to specify
+// network address of the remote server.
+//
+// Ignored if WithGRPCConn is provided.
+func WithNetworkAddress(v string) Option {
+	return func(c *cfg) {
+		if v != "" {
+			c.addr = v
+		}
+	}
+}
+
+// WithDialTimeout returns option to specify
+// dial timeout of the remote server connection.
+//
+// Ignored if WithGRPCConn is provided.
+func WithDialTimeout(v time.Duration) Option {
+	return func(c *cfg) {
+		if v > 0 {
+			c.dialTimeout = v
+		}
+	}
+}
+
+// WithGRPCConn returns option to specify
+// gRPC virtual connection.
+func WithGRPCConn(v *grpc.ClientConn) Option {
+	return func(c *cfg) {
+		if v != nil {
+			c.conn = v
+		}
+	}
+}